Estriol + Tretinoin Cream
Starting at $135/month
Estriol + Tretinoin Cream is a prescription topical formulation containing Estriol 0.3% and Tretinoin 0.01%, designed to improve hydration, texture, and overall skin quality. By combining bioidentical estriol with low-dose tretinoin, it supports estrogen-depleted skin while promoting gentle cellular renewal for improved comfort, smoothness, and resilience.
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Key Benefits:
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Helps relieve dryness and discomfort associated with low estrogen levels
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Improves skin texture and elasticity for a smoother, more supple appearance
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Supports collagen activity to soften the look of fine lines
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Enhances hydration and strengthens the skin barrier
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Promotes a more even tone and healthy-looking complexion
* Actual product packaging may appear differently than images shown on the website. Compounded drugs are permitted to be prescribed under federal law; however, the FDA does not review or approve compounded medications for safety or effectiveness. Benefits stated on You4You are based on 3rd party research.
Pricing Details
* Apply a thin layer (1g) of the cream to the affected area of the skin as directed by your healthcare provider.
* The cream should be gently massaged into the skin until it is fully absorbed.
30g - $135
90g - $245
* Can't ship to - Alabama, Louisiana, Puerto Rico, Washington DC
CLINICAL OVERVIEW
Unlike standard moisturizers, this prescription cream works at a biological level. Estriol 0.3% supports estrogen receptor activity in the skin, while Tretinoin 0.01% encourages controlled cell turnover. Together, they address hormonal skin changes and surface irregularities under clinician guidance with balanced tolerability.
HOW IT HELPS
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Restores Estrogen Signaling: Estriol 0.3% binds to epidermal estrogen receptors to support processes that decline with hormonal changes, improving skin comfort and function.
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Promotes Gentle Cellular Renewal: Tretinoin 0.01% supports controlled skin turnover, helping refine texture and smooth uneven areas without aggressive irritation.
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Supports Collagen & Elasticity: The combined formulation encourages dermal support over time, helping skin feel firmer and appear smoother with reduced fine lines.
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Improves Hydration & Tone: Enhances moisture retention and balanced renewal to reduce dryness and dullness, revealing calmer, more resilient skin.
Estriol
Balance + Comfort
Tretinoin
Renewal + Refinement
Your skin, fully renewed—no dullness, just glow.
About this Treatment
This comprehensive treatment plan covers everything you need. Once you begin, your first step will be an initial consultation with one of our certified physicians. During this session, they’ll work with you to determine the optimal approach for your hair journey, ensuring you receive the right medication and dosage. Your prescribed medication, along with all necessary supplies, will be shipped directly to you by one of our partnered pharmacies. Your package will include clear instructions on dosage, administration, and storage. You’ll have access to our experts at your convenience through our secure portal.
